Mobile vision screening system detects amblyopia with high sensitivity
01/30/2020
Zsófia Csizek1, Eszter Mikó-Baráth1, David P Piñero2, Kitti Szabó-Guth1, Péter Hegyi1, Ágota Pusztai3, Adrienne Csutak3, Gábor Jandó1
1 Institute of Physiology, University of Pécs, Medical School 2Department of Optics, Pharmacology and Anatomy, University of Alicante 3. Department of Ophthalmology, University of Pécs, Medical School
Dynamic random dot stereotest E (DRDSE) is part of an Android-based, innovative screening tool (EuvisionTab©) for the examination of stereovision, therefor for the detection of amblyopia and preamblyopic conditions. In the present study we evaluated its sensitivity and specificity of DRDSE compared to other stereotests. One hundred and thirty children were included between the ages of 4-13. A complete pediatric ophthalmological examination was performed. DRDSE was presented on a tablet. We used different densities of random dots composing the stimulus to set levels of difficulty: low density (LD 1% with noise) and very low density (VLD 0.7% without noise). In comparison, Lang II, TNO, Stereofly and Frisby stereotests were also performed. The computation of the predictive values and ROC analysis was performed for each stereotest. With refractive correction, DRDSE LD and VLD had a sensitivity of 91% and 87% for amblyopia, while the specificity was 71% in LD and 74% in a VLD. The sensitivity and specificity of the other stereotests were as follows: Lang II 82% and 91%, TNO 87% and 71%, Stereofly 82% and 82%, and Frisby 82% and 74%. DRDSE test is slightly more effective for the detection of amblyopia and preamblyopic factors compared to other stereotests. With the randomized order of image sequences, cloud-based data storage, and flexible settings, DRDSE may serve as an essential part of the state-of-the-art vision screening. Without refractive correction, which more resembles a real screening situation, the sensitivity of DRDSE LD and VLD were 91% and 100%, respectively. „SUPPORTED BY THE ÚNKP-19-3 NEW NATIONAL EXCELLENCE PROGRAM OF THE MINISTRY FOR INNOVATION AND TECHNOLOGY.” FEKUTSTRAT 2019: TEMPORARY REF. NO.: FIKP II. HUNGARIAN BRAIN RESEARCH PROGRAM 2.0 (NAP 2.0): 2017-1.2.1-NKP-2017-00002